The Trail Blazers were unable to build on their overtime win Sunday night versus Atlanta as they fell 107-99 on the road to the Sacramento Kings on Tuesday.
Portland got passed by in the second half, with the Kings beating them for only the second time in the last eight meetings.
The Blazers fell to 4-7 this season, 3-4 away.
The Kings improved to 4-6, including 2-3 at home.
Guards Damian Lillard and CJ McCollum paced Portland with 27 and 24 points, respectively. The only other Blazers in double figures were Hassan Whiteside with 17 points and starting small forward Kent Bazemore with 12.
Lillard was 6 of 10 from the field, 2 of 5 on 3-pointers. McCollum hit 11 of 21 shots, making 1 of 5 from outside the 3-point line.
For Sacramento, Bogdan Bogdanovic scored 25 points off the bench to augment the offense of starters Buddy Hield (20), Nemanja Bjelica (19), Harrison Barnes (16) and Richaun Holmes (11). Bjelica, a power forward, also had a game-high 12 rebounds.
The Kings had won three of their last four after an 0-5 start, but on Tuesday they were without starting point guard De'Aaron Fox, who sprained an ankle in practice on Monday and is likely to be out at least three weeks. He was averaging 19.8 points and 8.0 assists in the past six games. Veteran Cory Joseph took his place against the Blazers and scored three points, with three assists, in 37 minutes.
Each team owns a recent win over Atlanta; Sacramento beat the Hawks by 12 points, making 18 of 31 shots from 3-point range. Portland defeated the Hawks 124-113 in overtime with Lillard netting 30 points to go with seven rebounds and six assists.
The Blazers, after leading by 11 in the first quarter, had a 49-46 halftime lead, with neither team shooting particularly well. Oregon was at .462 overall and .267 from beyond the arc. Sacramento was at .367 and .211. Each team made four 3's in the half.
McCollum (15 points), Lillard (12) and Bazemore (10) carried Portland offensively. Anfernee Simons was 0 for 5 from the floor as part of a bench that totaled eight points in 47 minutes.
Simons ended the night 2 of 11and had five points in 27 minutes.
The Kings built a 14-point lead, 79-65, late in the third quarter, and finished the frame on top 81-70.
With six minutes to go, the Kings had a 96-82 advantage. Portland closed to within five points with just under three minutes remaining, but Sacramento scored a total of eight points on three consecutive posessions to lead 106-97 with heading inside the final minute.
The Blazers head back to Moda Center for a 7 p.m. Wednesday home game against the defending NBA champion Toronto Raptors, who dropped to 7-3 with a road loss to the Los Angeles Clippers on Monday.
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